An Easy and Direct Method for the Synthesis of 1,2,4-triazole Derivatives through Carboxylic Acids and Hydrazinophthalazine
نویسندگان
چکیده
We have developed an easy method for the synthesis of thirteen compounds derived from 1,2,4-triazoles through a carboxylic acid and hydrazinophthalazine reaction, with a 75-85% yield mediated by the use of agents such as 1-ethyl-3-(3 ́-dimethylaminopropyl)carbodiimide hydrochloride and 1-hydroxybenzotriazole. The operational simplicity of this method and the good yield of products make it valuable for the synthesis of new compounds with pharmacological activity.
منابع مشابه
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تاریخ انتشار 2008